«Brother Louie» is Modern Talking‘s first single from their third album, Ready for Romance. It is the fourth consecutive single to top the German Single Chart, after «You’re My Heart, You’re My Soul«, «You Can Win If You Want» and «Cheri, Cheri Lady«.

«Brother Louie» was released on 27 January 1986 and it peaked at No. 1 on March 3, 1986 in Germany. The single spent four weeks at the top and total of 17 weeks in the German single chart.In the UK, it peaked at No. 4 in the charts and went silver for selling over 250,000 units.»Brother Louie» was also certified silver in France for selling over 250,000 units.

In 1998, not long after the duo’s reunion, a re-worked version of the single was released entitled «Brother Louie ’98». The single, released in a new sleeve was also successful, it reached gold in France for selling over 250,000 units.